Article

Evaluation of Neonatal Cholestasis: An Experience in a Tertiary Centre of Bangladesh
Salahuddin Mahmud*, , Jahida Gulshan, Mashud Parvez, Farhana Tasneem, Syed Shafi Ahmed

Details

Author

Salahuddin Mahmud*,

ISSN

Applied

DOI

doi.org/10.5281/zenodo.4007594

Published on

Aug 29, 2020

Abstract

A common presenting feature of neonatal hepatobiliary and metabolic dysfunction is cholestatic jaundice. Any infant who remains with jaundice beyond age 2 to 3 weeks must be assessed with fractionated serum bilirubin level. Late referral and lack of exact etiological diagnosis results in poor outcome in a substantial number of cases in Bangladesh. Objective: Retrospective evaluation of infants with cholestatic jaundice in terms of history, common clinical presentation and biochemical profile with etiologies. Materials & Methods: The study was conducted in the Department of Pediatric Gastroenterology, Hepatology & Nutrition, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh from July 2014 to June 2016 on 80 infants who were presented with cholestatic jaundice at

Keywords

Neonatal cholestasis, Biliary atresia, Idiopathic neonatal hepatitis, Liver biopsy (LB).